My laboratory integrates quantitative genetics, bioinformatics and behavioral science to understand and identify the biological basis for the relationships among behavioral traits. We develop and apply cross-species genomic data integration, advanced computing methods, and novel high-precision, high-diversity mouse populations to find genes associated with a constellation of behavioral disorders and other complex traits. This integrative strategy enables us to relate mouse behavior to specific aspects of human disorders, to test the validity of behavioral classification schemes, and to find genes and genetic variants that influence behavior.
The tools and approaches we have devised are applicable to other common and rare diseases, and are part of an integrated suite of capabilities for biomedical researchers.
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Contact Information
Program & Lab Contact: [email protected]
Administrative Contact: [email protected]