News Releases

New JAX-led course gives early career researchers a front-row seat to personalized cancer care

Genomic tumor boards connect early career researchers with real-world cancer cases and clinical decision-making

Exploring brain plasticity with single-cell precision

Simons Foundation supports innovative research at JAX to understand aging and cognitive decline

Neal Milch elected chair of The Jackson Laboratory Board of Trustees

A ‘universal’ therapy against the seasonal flu? Antibody cocktail targets virus weak spot

Unusual immune strategy protects against all tested flu strains and prevents viral escape.

Could routine eye exams reveal early signs of Alzheimer’s?

New findings strengthen the link between retinal health and early dementia risk.

Study uncovers molecular “switch” behind chemoresistance in blood cancer

JAX scientists are beginning to understand how RNA biology affects resistance to chemotherapy in acute myeloid leukemia.

Gut microbiome may predict invisible chronic fatigue syndrome and long COVID

New research from The Jackson Laboratory and partners reveals that chronic fatigue syndrome (ME/CFS) and long COVID may leave detectable biological fingerprints in the body — providing hope for future diagnostic tools.

The most complete view of the human genome yet sets new standard for use in precision medicine

What if scientists unlocked the most hidden, hardest-to-read regions of our DNA?

Genome editing corrected rare brain mutations in mice. Could it help fight neurological diseases?

Scientists have successfully corrected gene mutations in mice with an ultra-rare disease by editing DNA directly in the brain using a single injection. This technique, which also showed promise in patient-derived cells, addressed mutations causing alternating hemiplegia in childhood (AHC), reducing symptoms and extending survival in affected mice.

What rare diseases can teach us about the rest of medicine

Why genetic outliers might hold the key to common conditions—and why we should invest more in understanding them

Pioneering alliance between The Jackson Laboratory and The New York Stem Cell Foundation ushers in new era of predictive biomedical research

Uniting cutting-edge genomics, stem cell science, and AI-enabled data science to accelerate the discovery of life-changing therapies

Mouse models for ultra-rare disorder could pave the way for nervous system gene editing therapies

The models offer clear insights into how alternating hemiplegia of childhood progresses—and how it might be stopped.

Inaugural UConn-JAX symposium showcases the power of AI to transform medicine and biomedical research

Researchers gather for inaugural symposium to explore how artificial intelligence is accelerating discovery, improving diagnostics, and transforming patient care.

Why patients with mitochondrial disease more susceptible to infections

A discovery at The Jackson Laboratory reveals how dysfunctional mitochondria put the immune system on overdrive, leading to severe infections.

Supercharged mitochondria spark aging-related blood disorders

As we age, blood stem cells can accumulate genetic mutations, leading to serious health conditions. Researchers at The Jackson Laboratory have discovered that a common mutation in the gene Dnmt3a enhances mitochondrial function in these cells, promoting clonal hematopoiesis, which increases the risk of heart disease and blood cancers.

New study uncovers how genes influence retinal aging and brain health

Scientists discover how to reactivate cancer’s molecular “kill switch”

Discovery could open door to game-changing RNA-based multi-cancer therapeutics.

Forum highlights innovations in diagnostics & treatments

Scientists, patients, advocates, legislators, industry leaders and investors convened to highlight collaborative efforts and technological advances in rare disease research.

JAX and University of New England launch applied genomics course

The Jackson Laboratory and University of New England launch applied genomics course to advance personalized medicine.

Landmark atlas reveals how aging breast tissue shapes breast cancer risk

JAX researchers have uncovered how age-related cellular and molecular changes may contribute to breast cancer development.

Mary Dickinson appointed to co-chair Maine AI Task Force

Healthcare leaders and executives in Maine selected to guide governor on AI innovation and workforce development.

JAX celebrates a year of important achievements in genetics & genomics

The Jackson Laboratory (JAX) achieved groundbreaking scientific milestones in 2024, securing record grant funding, publishing 385 research papers, and earning the highest-ever NCI rating for its Cancer Center. From genomic medicine to AI-driven discoveries, JAX continues to revolutionize biomedical research, drug discovery, and precision healthcare.

JAX researchers alleviate symptoms of ultra-rare genetic disease

Combining genetic therapy and bone marrow transplantation may offer comprehensive treatment solution for multiple sulfatase deficiency.

CAST mouse model: A crucial tool for future Covid-19 outbreaks

Researchers at The Jackson Laboratory and Trudeau Institute have identified the first mouse strain that is susceptible to severe COVID-19 without the need for genetic modification.

JAX joins ARPA-H projects to transform personalized medicine through AI-driven cancer and prescription drug research

The Jackson Laboratory is a partner in two major projects funded by the Advanced Research Projects Agency for Health (ARPA-H), with a combined $60 million investment aimed at advancing biomedical research through data-driven approaches and AI.

The Jackson Laboratory and Allentown unveil a revolutionary AI-driven home-cage monitoring solution set to transform preclinical research

The AI-powered home-cage monitoring solution is poised to enhance preclinical research efficiency and improve the translation of findings to clinical settings.

JAX researchers unveil method to map immune cell connections, predicting patient survival in cancer

Researchers at The Jackson Laboratory have developed a new combination of imaging and computational methods to study connections between immune cells in breast cancer and melanoma.

Researchers flip genes on and off with AI-designed DNA switches

Researchers at The Jackson Laboratory (JAX), the Broad Institute of MIT and Harvard, and Yale University, have used artificial intelligence to design thousands of new DNA switches that can precisely control the expression of a gene in different cell types.

JAX researchers call for genetically diverse models to drive innovation in drug discovery

Diverse mouse models show promise in how we understand and treat diseases, offering a significant improvement over standardized but limited mouse and cellular models.

Study probes how eating less can extend lifespan

Researchers at The Jackson Laboratory conduct pivotal study into aging and lifespan to uncover new details about how diets might make people live longer — but also their negative side effects.

How diabetes risk genes make cells less resilient to stress

Some genetic factors predisposing people to diabetes might change the way pancreatic cells respond to molecular stress, researchers at The Jackson Laboratory discovered.

$1.6 million NIH grant fuels JAX’s mass spectrometry capabilities to decode complex diseases

The new funding will help support the first-of-its-kind single-cell mass spectrometer in Maine, and one of the first in the country.

JAX celebrates heart education & research with completion of a course

Through interactive, case-based lessons, the series empowers cardiology clinicians to move beyond a one-size-fits-all approach, enabling them to adopt more targeted management strategies for their patients.

Chief Scientific Officer Mary Dickinson inducted into the American Association for the Advancement of Science

Dickinson among 502 Fellows honored for scientifically or socially distinguished efforts to advance science or its application at a ceremony in Washington, D.C.

Unravel Biosciences and JAX announce collaboration

Unravel Biosciences and The Jackson Laboratory announce collaboration to accelerate the discovery of promising drugs for diseases with high unmet need.

Charles Lee elected to the Royal Society of Canada

This recognition by the Society is its highest honor in the academic fields of arts, social sciences, humanities and sciences.

Researchers are closing in on a mouse model for late-onset Alzheimer’s research

The Jackson Laboratory breakthrough could accelerate efforts to understand and treat dementia.

Researchers develop stress-free method to weigh mice using computer vision

The Jackson Laboratory has developed a computer vision-based method to accurately and continuously measure mouse body mass, offering a new resource for researchers that promises to enhance the quality of a wide range of preclinical studies.

New analysis offers most comprehensive roadmap to date for more targeted Alzheimer’s research and drug discovery

Research offers first ranking of relative role and significance of every known gene and protein in development of Alzheimer's.

Study reveals potential therapeutic role of sodium valerate in reducing binge drinking

The role of gut-brain interaction in developing new alcohol use disorder treatments.

How old is your bone marrow?

Hematopoietic stem cells age differently in genetically identical mice, offering new pathways for interventions to preserve health with aging.

Reinvigorating exhausted immune cells reveals potential therapy target for cancer

Reengergizing exhausted T cells can kickstart immune system to fight cancer.

The Jackson Laboratory creates mice that better reflect human genetic variation

Wild-derived mice could make it easier to draw conclusions about the effectiveness of new treatments or pharmaceuticals in humans.

The Jackson Laboratory and AbTherx Announce Partnership to Enhance Therapeutic Antibody Discovery

Partnership to expedite antibody discovery and derisk the development of vital new therapies.

The Jackson Laboratory appoints Mary Dickinson as chief scientific officer

Dickinson's research background coupled with her successful executive leadership will help drive major initiatives and research priorities at a time of rapid growth.

Study indicates that cancer patients gain important benefits from genome-matched treatments

Maine cancer patients experienced better outcomes following genomic tumor testing to guide targeted therapy strategies; but a gap between testing and clinical delivery still exists.

The Jackson Laboratory receives $8 million in federal funding to expand research capacity in rare diseases

The funding will support construction of a dedicated facility for rare disease research, marking the first expansion of the Bar Harbor research footprint in seven years.

JAX researchers make mice a more powerful tool to study a wide range of human diseases

A new protocol sets the stage for researchers to directly compare mouse and human cells to more closely approximate human health conditions.